News

Media attention | Yu Qiang: the entrepreneurial path of "veterans" in the pharmaceutical industry

  • Categories:Company News
  • Author:
  • Origin:
  • Time of issue:2022-09-24
  • Views:0

(Summary description)On August 8, the first domestic terifluoramine tablets developed by Shengshi Tyco were put on the market, bringing new choices and drug supply guarantees for domestic patients with multiple sclerosis.

Media attention | Yu Qiang: the entrepreneurial path of "veterans" in the pharmaceutical industry

(Summary description)On August 8, the first domestic terifluoramine tablets developed by Shengshi Tyco were put on the market, bringing new choices and drug supply guarantees for domestic patients with multiple sclerosis.

  • Categories:Company News
  • Author:
  • Origin:
  • Time of issue:2022-09-24
  • Views:0

On August 8, the first domestic terifluoramine tablets developed by CGeneTech were put on the market, bringing new choices and drug supply guarantees for domestic patients with multiple sclerosis.

In this regard, Yu Qiang, founder and CEO of CGeneTech Biomedical Technology (Suzhou) Co., Ltd., was gratified and said that after more than ten years of running, the company finally took the first step in the long march.

In May 2018, multiple sclerosis was included in the first batch of rare diseases in China.

Yu Qiang said that in fact, rare diseases are not rare. But there is no medicine to cure, which is the unspeakable pain of patients with rare diseases. The earlier multiple sclerosis is diagnosed and treated, the better it can relieve symptoms and delay disease development.

CGeneTech was founded in Suzhou Industrial Park in 2010. Its core team has decades of experience in the whole life cycle of international drugs and is committed to the research, development and industrialization of small molecule innovative drugs for breakthrough therapies. Relying on the integrated drug R&D technology platform and diversified business vision, the company has built a rich pipeline of innovative drugs, covering many disease fields such as hypoglycemic, anti-cancer and rare diseases.

Yu Qiang has a solid academic background in the field of chemistry. He has successively obtained bachelor's, master's and doctor's degrees in chemistry from Peking University, Kansas State University to the University of Kansas. After graduation, he worked in the pharmaceutical chemical technology company for many years, and successfully founded a company to develop new drug molecular modules. After nearly 20 years of overseas career, he returned to China in 2010 and co founded CGeneTech with Mr. Ding Juping, who has rich experience in new drug research and development and application.

Yu Qiang has always been accompanied by the three soul questions of "why do you want to return to China to start a business", "why do you want to choose Suzhou to start a business", and "how difficult it is to start a business". He always gives standard answers to the first two, but has no answer to the last one.

Talking about why he returned to China to start a business, Yu Qiang explained: "there are two main reasons. First, around 2008, we found a series of active compounds aimed at DPP-IV, the target of diabetes, and hoped to promote R & D and industrialization as soon as possible. At that time, the domestic support and entrepreneurial environment for returnees, especially the policies on biomedicine, were becoming more and more mature."

In addition, it is Yu Qiang's wish to let domestic patients use affordable good drugs and new drugs, which is also an important factor in his choice to return to China to start his own business. "This is a right choice made at the right time. China is full of changes, opportunities and challenges. I think there is much to be done."

"The decision to come to Suzhou to start a business was convinced by the emails. When I was still in the United States, I asked the Suzhou Industrial Park government about entrepreneurship and received professional replies. I felt that my English was better than mine, which made me curious about Suzhou." When Yu Qiang set foot on the land of Suzhou, he found that Suzhou, where "everyone sleeps on the river", has a strong innovation ability.

Now, Yu Qiang has been dormant on the thorny road of entrepreneurship for more than ten years. He found that in addition to being very livable, Suzhou also provided considerate care and precise services for talents, and was able to take into account various pain points in the growth process of biomedical innovative enterprises, providing a variety of preferential policies.

How difficult is entrepreneurship? Yu Qiang said that this is a question in the present continuous tense and there is no answer. In his own words, this is the "Long March" of China's bio pharmaceutical industry. Once given up, it means that all previous efforts and sacrifices have been wasted.

"2015 has been the hardest year so far." Yu Qiang recalled that when he started his business in China, his income was very low, and it was very difficult for the company to raise funds. He did not have enough money for clinical trials. In 2015, the company had capital problems, and the brain drain was serious. All the people who wanted to recruit did not come to the company when they were offered an offer. That year was really tough.

Many years later, looking back on that period of time, Yu Qiang said that "feelings are a kind of power". He said that the original intention of driving himself to complete this road was to "let domestic patients use affordable good drugs and new drugs. I never thought of giving up. If I gave up, all the efforts ahead, including the sacrifices made by my family, would not be worth it."

"A general's success will wither away." Yu Qiang lamented that many returned scientific researchers in the past, after experiencing the difficulties of entrepreneurship, still fell behind the long cycle of drug research and development, huge investment in research and development, and extremely low success rate of research and development. This is exactly one of the fundamental reasons why VCs were not keen on this field in the past few years. After all, after the investment, they may face long-term problems such as no take-up and blocked exit channels, which obviously means "no money" for institutions. This has made returned entrepreneurs suffer from a shortage of funds.

"I am lucky. As long as I am still running on the road, there is hope." Since his return to China, Tyco has been developing along the path of "me too to me first", and its clinical applications have increased year by year. Up to now, CGeneTech has accumulated nearly 600 million yuan of financing.

Yu Qiang said that he just wanted to take the team to every step. Keep moving forward, do not stay mediocre, let alone fall behind. It feels like a long-distance race. You must hold on to the leader. You must be in the first echelon. In the first echelon, you will have the opportunity to surpass.

Yu Qiang is jokingly called the best poet in the medical field, and the best poet in the poetic field. Drug research and development is like the creation of ancient poetry. Medicine is in poetry, and poetry is in people's hearts. Suzhou has been favored by literati since ancient times, whether it is the landscape of small bridges, flowing water and people's homes, or the exquisite taste of Jiangnan. All this has provided Yu Qiang with spiritual comfort.

                                                                                                                                                      Source: China News Network Author: Zhou Jianlin

Shengshi

Shengshi Taike: Exchange 'One Promise, One Thousand Gold' for 'Dreams Come True'

Introduction: Adhere to our original aspiration, forge ahead, and let our dreams shine into reality. The rapid development of Suzhou Industrial Park is the result of generations of park residents' continuous efforts, and also embodies the strength of each enterprise's rooting and growth. Enterprises are witnesses, but also participants. In the park, one group after another of enterprises have run the "upward trend" with their own "hard skills", using abundant vitality as ink and strong resilience as pen, writing a wonderful chapter of "striving for thirty years and building dreams towards the future". On the occasion of 15 years of rooting in Suzhou Industrial Park, Shengshi Taike Biopharmaceutical Technology (Suzhou) Co., Ltd. has reached a major development milestone - the company's first independently developed Class 1 innovative drug, sitagliptin phosphate tablets, has been approved for listing in China. The founder and CEO of Shengshi Taike, Yu Qiang, wrote a poem with deep emotion: "The trees and trees are all singing in heaven, and the colors are shining in the hall. The morning sun shines on the clouds, and the prosperous era welcomes the sunrise The original intention of entrepreneurship and the passion for innovation are intertwined at this moment into a beautiful story of the "two-way rush" between the park and talents. The successful approval of sengliptin for listing is due to the entrepreneurial fertile ground of Suzhou and the park, as well as the strong support of many departments. It is also a way to repay the park's pro business services with our innovative drugs, "said Yu Qiang. Since settling in the park in 2010, Shengshi Taike has been based in Suzhou and has a global perspective, focusing on the research and production of small molecule innovative drugs. With an integrated drug research and development technology platform and diversified business vision, it has built a rich pipeline of innovative drugs covering areas such as blood sugar reduction, anti-cancer, and autoimmune。 Funds - the 'first pot of gold' that leverages innovation leverage In 2010, with rich scientific research and practical experience in the field of pharmaceutical research and development, Yu Qiang and partner Ding Juping established Shengshi Taike in Suzhou Biomedical Industry Park (BioBAY), committed to the research and industrialization of breakthrough small molecule innovative drugs for therapeutic purposes. "China is a big country with diabetes in the world, and the number of patients with diabetes is the first in the world. In 2008, I heard the news that China began to attach importance to the biomedical industry. Around 2010, I decided to bring my initial research and development achievements, raise funds, form a team, and return to China to make a new class of hypoglycemic drugs." Recalling more than a decade ago, Yu Qiang still remembers. The decision to return to China and start a business in the park was impressed by the numerous emails exchanged. At that time, I was still in the United States and consulted the park government about entrepreneurship issues through email. The response I received was not only fluent in English, but also highly professional. The fact has proven that my initial choice was the right one The beginning of everything is difficult. Even if the conditions for starting a business in China are relatively mature, for a new drug research and development company in the start-up stage, the challenges it faces can be imagined. Shortage of funds is the first problem. Fortunately, the park provides very strong financial support to leading talents, "said Yu Qiang. When he settled in 2010, the park could offer a" big gift package "of up to 10 million yuan to leading talents in the biopharmaceutical field, including housing subsidies, rent reductions, subsidized loans, start-up capital, etc. More importantly, the predecessor of Yuanhe Holdings, Zhongxin Venture Capital, gave us 6.5 million yuan in angel investment, which can be said to be a" timely help "for start-up companies. Later, the company's new drugs were successively shortlisted for the national "Twelfth Five Year Plan", "Thirteenth Five Year Plan" and "Major New Drug Creation" special projects, and were included in the national key support track, further obtaining financial support. The guidance fund and leading venture capital of the park's enterprise development service center have provided financing support at different stages of Shengshi Taike's development. With the guidance of government industry funds, they have also attracted more social capital to invest and jointly support enterprise innovation. I have always believed that it is the '1' given by the park that leads to the '0' increase in social capital in the future, "Yu Qiang said with a smile. Funds support the growth of enterprises and drive industrial development. At present, Shengshi Taike has built a rich drug pipeline, with product distribution fr
2025-01-07
Milestones

Milestones | Shengshi Taike's new generation DPP-4 inhibitor approved for market launch

Today, the official website of the National Medical Products Administration (NMPA) of China announced that Shengshi Taike's independently developed Class 1 innovative drug, saxagliptin phosphate tablets (formerly known as saxagliptin phosphate tablets), has been approved for market in China. This is a new generation of highly selective DPP-4 inhibitor, which is suitable for improving the blood sugar control of adult type 2 diabetes patients. According to the Guidelines for the Prevention and Treatment of Type 2 diabetes in China, the prevalence of diabetes among adults in China has risen to 11.2%, of which more than 90% are type 2 diabetes. In order to meet the huge clinical demand, some new drugs with different mechanisms of action from traditional oral hypoglycemic drugs have emerged in recent years. Dipeptidyl peptidase-4 (DPP-4) inhibitors are one of them. They not only improve hyperglycemia, but also are not easy to induce hypoglycemia and weight gain. They have the characteristics of rapid oral absorption, long half-life, and long-lasting effect, and are known as "smart" hypoglycemic drugs. Currently, they have been recommended by many domestic and foreign guidelines. As a new generation of highly selective DPP-4 inhibitor independently developed by Shengshi Taike, sengliptin has been continuously selected for the national "Major New Drug Development" special projects in the 12th and 13th Five Year Plans. Due to the excellent data demonstrated in the first phase clinical trial of the best product in the market, it was exempted from phase 2 clinical trials and directly entered phase 3 clinical trials, pioneering the "exemption from two to three" clinical trials in the field of this drug. The results of the phase III clinical trial of Sengliptin led by Professor Ji Linong, director of the Endocrinology Department of Peking University People's Hospital and director of Peking University diabetes Center, showed that in the single drug treatment trial of Sengliptin, the reduction values of HbA1c in the 50mg and 100mg dose groups at the end of the 24th week were 1.08% and 1.07% respectively; In the treatment trial of sengliptin combined with metformin, the glycated hemoglobin decreased by 1.23% and 1.17% in the 50mg and 100mg dose groups at the end of the 24th week, respectively. Meanwhile, both sets of experimental data showed that patients with higher blood sugar levels experienced a greater decrease in glycated hemoglobin levels. In addition to its excellent hypoglycemic effect, what is even more commendable is that in the comparison between the 100mg dose group (high-dose group) and the placebo group in the last 28 weeks, the incidence of adverse reactions of sengliptin is similar to that of the placebo group, and its safety further solves the common adverse reactions in marketed products. At present, metformin combined with leptin has become the main treatment scheme in the clinical application of treating type 2 diabetes. According to Sullivan's research report, by 2030, the market size of leptin in China will exceed 30 billion, with broad market prospects. Ding Juping, the co-founder and president of Shengshi Tyco, said: "I am very glad to see the company's self-developed product, Sengliptin Phosphate Tablets, has been approved for listing. This drug will be the best new hypoglycemic drug of its kind with half the effort and twice the treatment effect. I hope it will benefit the majority of diabetes patients in China as soon as possible after it is approved for listing." Dr. Yu Qiang, the founder and CEO of Shengshi Tyco, said: "Sengliptin's successful approval for listing benefits from Suzhou and the park as a fertile land for entrepreneurship and the strong support of many departments. It is also a" promise of gold "to use our innovative drugs to repay the business friendly services in Suzhou Park. At this moment, I would like to use an original poem to bless this new drug for its successful launch." Morimu's sounds of nature are listed in the palace. The morning light shines on the clouds, and the prosperous world welcomes the sunrise.
2024-12-05

Contact Us

Add:Room 101, Bld C11, 218 Xinghu Rd,Suzhou industrial Park,China, 215123

Tel: +86-512-62956960(Recruitment)

         +86-512-62956961(marketing)

Copyright © 2022  CGeneTech (Suzhou, China) Co., Ltd.  All rights reserved.  苏ICP备2022006552号-1  Powered by 300.cn  SEO