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Shengshi Taike has once again been listed on the "Top 50 Most Influential Medical and Health Enterprises in China" list

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  • Time of issue:2024-05-17
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(Summary description)Recently, CHC Medical Consulting and CITIC Securities officially released the "2023 China Healthcare Industry Investment and Financing Honor List". As an innovative pharmaceutical company in the commercialization stage, Shengshi Taike has once again been listed in this category and won the honor of being one of the top 50 most influential medical and health enterprises in China in 2023.

Shengshi Taike has once again been listed on the "Top 50 Most Influential Medical and Health Enterprises in China" list

(Summary description)Recently, CHC Medical Consulting and CITIC Securities officially released the "2023 China Healthcare Industry Investment and Financing Honor List". As an innovative pharmaceutical company in the commercialization stage, Shengshi Taike has once again been listed in this category and won the honor of being one of the top 50 most influential medical and health enterprises in China in 2023.

  • Categories:Company News
  • Author:
  • Origin:
  • Time of issue:2024-05-17
  • Views:0

Recently, CHC Medical Consulting and CITIC Securities officially released the "2023 China Healthcare Industry Investment and Financing Honor List". As an innovative pharmaceutical company in the commercialization stage, Shengshi Taike has once again been listed in this category and won the honor of being one of the top 50 most influential medical and health enterprises in China in 2023.

The Annual China Healthcare Industry Investment and Financing Honor List is jointly launched by CHC Medical Consulting and CITIC Securities, and is an authoritative ranking in the healthcare field from a third-party perspective. Since the release of the first list in 2018, the Honor List selection has become one of the important indicators for the development and investment and financing of China's medical and health industry. The release of the Honor List is not only a recognition and recognition of the contributors to the value of the healthcare industry, but also an encouragement and motivation for the entire industry, reflecting the positive values and positive energy within the industry.

Shengshi Taike was once again selected as one of the top 50 most influential medical and health enterprises in China this year. Despite facing challenges in the industry in the past two years, it has continued to achieve innovative results. At the beginning of last year, the company independently developed a new generation of highly selective DPP-4 inhibitor, Sengliptin (formerly known as Shenggliptin), and the NDA application was accepted by the National Medical Products Administration. Professor Ji Linong, an internationally renowned diabetes expert and the director of the Department of Endocrinology of Peking University People's Hospital, announced the data and results of the phase III clinical trial of Sengliptin. The data showed that compared with the similar drugs that have been marketed, the treatment effect of Sengliptin is expected to be the best hypoglycemic drug of its kind in terms of "quantity" and "half power". Even more valuable is that its safety further solves the common adverse reactions in products already on the market. At present, this product has entered the final review stage, and after its successful launch, it will provide more effective and safe optimal hypoglycemic programs for patients in China, a large country with diabetes. At the same time, the company has also carried out a comprehensive layout of oral drugs and derivative diseases around the global mainstream target of diabetes.

In the field of cancer, the company has already entered the clinical stage with four of its anti-cancer drugs under research, and two have completed the dual reporting between China and the United States, marking a solid step for the company's innovative drugs to go global. Among them, CGT-1881 is a CXCR4 targeted drug that has attracted global attention, used in the field of hematopoietic stem cell mobilization and other therapeutic fields. It is the only original small molecule oral CXCR4 antagonist in China, which can provide patients with better medication compliance. CXCR4 (chemokine receptor), as a popular target for global research and development, not only plays a key role in tumors, but also has close relationships with some immune diseases, genetic diseases, and viral diseases. At present, CGT-1881 is steadily advancing clinical trial research in healthy subjects, non Hodgkin's lymphoma or multiple myeloma patients.

Shengshi Taike was founded in Suzhou Industrial Park in 2010. The core team has decades of experience in the entire lifecycle of international drugs and is committed to the research and industrialization of high-quality and differentiated small molecule innovative drugs. With an integrated drug research and development technology platform and a diversified business perspective, the company has built a rich pipeline of innovative drugs, covering multiple disease fields such as hypoglycemic, anti-cancer, and autoimmune.

Milestones

Milestones | Shengshi Taike's new generation DPP-4 inhibitor approved for market launch

Today, the official website of the National Medical Products Administration (NMPA) of China announced that Shengshi Taike's independently developed Class 1 innovative drug, saxagliptin phosphate tablets (formerly known as saxagliptin phosphate tablets), has been approved for market in China. This is a new generation of highly selective DPP-4 inhibitor, which is suitable for improving the blood sugar control of adult type 2 diabetes patients. According to the Guidelines for the Prevention and Treatment of Type 2 diabetes in China, the prevalence of diabetes among adults in China has risen to 11.2%, of which more than 90% are type 2 diabetes. In order to meet the huge clinical demand, some new drugs with different mechanisms of action from traditional oral hypoglycemic drugs have emerged in recent years. Dipeptidyl peptidase-4 (DPP-4) inhibitors are one of them. They not only improve hyperglycemia, but also are not easy to induce hypoglycemia and weight gain. They have the characteristics of rapid oral absorption, long half-life, and long-lasting effect, and are known as "smart" hypoglycemic drugs. Currently, they have been recommended by many domestic and foreign guidelines. As a new generation of highly selective DPP-4 inhibitor independently developed by Shengshi Taike, sengliptin has been continuously selected for the national "Major New Drug Development" special projects in the 12th and 13th Five Year Plans. Due to the excellent data demonstrated in the first phase clinical trial of the best product in the market, it was exempted from phase 2 clinical trials and directly entered phase 3 clinical trials, pioneering the "exemption from two to three" clinical trials in the field of this drug. The results of the phase III clinical trial of Sengliptin led by Professor Ji Linong, director of the Endocrinology Department of Peking University People's Hospital and director of Peking University diabetes Center, showed that in the single drug treatment trial of Sengliptin, the reduction values of HbA1c in the 50mg and 100mg dose groups at the end of the 24th week were 1.08% and 1.07% respectively; In the treatment trial of sengliptin combined with metformin, the glycated hemoglobin decreased by 1.23% and 1.17% in the 50mg and 100mg dose groups at the end of the 24th week, respectively. Meanwhile, both sets of experimental data showed that patients with higher blood sugar levels experienced a greater decrease in glycated hemoglobin levels. In addition to its excellent hypoglycemic effect, what is even more commendable is that in the comparison between the 100mg dose group (high-dose group) and the placebo group in the last 28 weeks, the incidence of adverse reactions of sengliptin is similar to that of the placebo group, and its safety further solves the common adverse reactions in marketed products. At present, metformin combined with leptin has become the main treatment scheme in the clinical application of treating type 2 diabetes. According to Sullivan's research report, by 2030, the market size of leptin in China will exceed 30 billion, with broad market prospects. Ding Juping, the co-founder and president of Shengshi Tyco, said: "I am very glad to see the company's self-developed product, Sengliptin Phosphate Tablets, has been approved for listing. This drug will be the best new hypoglycemic drug of its kind with half the effort and twice the treatment effect. I hope it will benefit the majority of diabetes patients in China as soon as possible after it is approved for listing." Dr. Yu Qiang, the founder and CEO of Shengshi Tyco, said: "Sengliptin's successful approval for listing benefits from Suzhou and the park as a fertile land for entrepreneurship and the strong support of many departments. It is also a" promise of gold "to use our innovative drugs to repay the business friendly services in Suzhou Park. At this moment, I would like to use an original poem to bless this new drug for its successful launch." Morimu's sounds of nature are listed in the palace. The morning light shines on the clouds, and the prosperous world welcomes the sunrise.
2024-12-05

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