Dr. Yu Qiang of CGeneTech was interviewed by "Science and Technology Source Power" of First Financial Group

Categories:Media
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Origin:科创源动力
Time of issue:2021-12-20
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(Summary description)Recently, the "Source Dynamics of Science and Technology Innovation" column presented by China Business News and WeChat Bank went to Suzhou Industrial Park to explore the upgrading path of "Made in Suzhou" and analyze the "source dynamics" behind the rapid development of Suzhou's science and technology innovation enterprises together with Yang Yudong, Editor-in-Chief of China Business News, Wang Qiangbin, Executive Vice Director of Suzhou Institute of Nanotechnology and Nanobiont, Chinese Academy of Sciences, Li Wei, Deputy Director of Institute of Applied Economic Research, Shanghai Academy of Social Sciences, Fei Jianjiang, Managing Partner of Suzhou Industrial Park Yuanhe Origin Venture Capital Co.

Dr. Yu Qiang of CGeneTech was interviewed by "Science and Technology Source Power" of First Financial Group

(Summary description)Recently, the "Source Dynamics of Science and Technology Innovation" column presented by China Business News and WeChat Bank went to Suzhou Industrial Park to explore the upgrading path of "Made in Suzhou" and analyze the "source dynamics" behind the rapid development of Suzhou's science and technology innovation enterprises together with Yang Yudong, Editor-in-Chief of China Business News, Wang Qiangbin, Executive Vice Director of Suzhou Institute of Nanotechnology and Nanobiont, Chinese Academy of Sciences, Li Wei, Deputy Director of Institute of Applied Economic Research, Shanghai Academy of Social Sciences, Fei Jianjiang, Managing Partner of Suzhou Industrial Park Yuanhe Origin Venture Capital Co.

Categories:Media
Author:
Origin:科创源动力
Time of issue:2021-12-20
Views:0

　　Recently, the "Source Dynamics of Science and Technology Innovation" column presented by China Business News and WeChat Bank went to Suzhou Industrial Park to explore the upgrading path of "Made in Suzhou" and analyze the "source dynamics" behind the rapid development of Suzhou's science and technology innovation enterprises together with Yang Yudong, Editor-in-Chief of China Business News, Wang Qiangbin, Executive Vice Director of Suzhou Institute of Nanotechnology and Nanobiont, Chinese Academy of Sciences, Li Wei, Deputy Director of Institute of Applied Economic Research, Shanghai Academy of Social Sciences, Fei Jianjiang, Managing Partner of Suzhou Industrial Park Yuanhe Origin Venture Capital Co.

With a complete set of services from policy, talent, information, to capital, Suzhou has attracted many high-tech enterprises. Dr. Yu Qiang, CEO of Centec Biomedical Technology (Suzhou) Co., Ltd. said in an interview with the columnist that besides being very livable, Suzhou is also very considerate to talents and precise services, and can consider various pain points of biomedical innovative enterprises in the process of growth and provide various policy benefits.

　　Innovation starts with industry, and industry changes because of innovation. Suzhou's "manufacturing gene", which has been passed down from generation to generation, is driving the engine of innovation, drawing the blueprint for industrial upgrading and gathering more and more talents.

　　This is the best expression of the value and power of finance, which supports the growth of enterprises, drives the development of industries, and supports economic growth. With the combined efforts of government, capital, talents and industry, the innovation power of a city will continue to surge.

　　Link to original article: First Financial. From a thousand-year old capital to a city of innovation, decoding the driving force of science and innovation behind Suzhou. https://m.yicai.com/news/101262719.html,2021-12-19

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New generation of highly selective DPP-4 inhibitors international diabetes expert Professor Ji Linong interprets Shengglitin Phase III clinical data

2023-05-31

The world's first SGLT-2/DPP-4 dual target inhibitor with complementary advantages has been approved for clinical use

Recently, Shengshi Taike's Class 1 innovative drug SGLT-2/DPP-4 dual target inhibitor CGT-2201 has been granted implicit permission for clinical trials by the National Drug Administration. CGT-2201, which targets SGLT-2 and DPP-4, two important targets related to glucose metabolism, can be better used for the treatment of diabetes and its derivatives, including diabetes nephropathy and non-alcoholic fatty liver disease. In 2021, the number of diabetes patients in China will reach 141 million, ranking first in the world. Among the numerous patients with diabetes in China, 20-40% may suffer from complications of diabetes nephropathy. Among the existing hypoglycemic drugs, only sodium glucose cotransporter 2 (SGLT-2) inhibitor has significant renal protection effect in clinical verification, but its inherent reproductive and urinary system infection risks limit its use. Based on SGLT-2 inhibitors and combined with the characteristics of dipeptidyl peptidase 4 (DPP-4) inhibitors, we design and develop a drug that can improve blood sugar, reduce side effects of urinary and reproductive system infections, is not limited by renal function, and has kidney benefits. It is expected to fill the market gap and meet the needs of patients. Based on this market background and target characteristics, Shengshi Taike utilizes its own small molecule chimera drug technology platform to develop multi head multifunctional new drug products with synergistic mechanisms, with CGT-2201 being one of its representative works. It fuses the respective mechanism characteristics of SGLT-2 and DPP-4. On the basis of inhibiting the activity of SGLT-2 to reduce the reabsorption of glucose in the kidney, it also slows down the inactivation of DPP-4 on GLP-1, playing a dual role mechanism to play a superposition effect; While achieving considerable hypoglycemic effect, it can reduce the side effects of existing SGLT-2 drug urinary system infection; At the same time, without kidney excretion, it can reduce the burden of the kidney and reduce the contraindication of diabetes patients with renal insufficiency. Therefore, this drug will have the advantage of better controlling blood sugar and protecting patient kidney function. Shengshi Tyco was founded in Suzhou Industrial Park in 2010. Its core team has decades of experience in the whole life cycle of international drugs, and is committed to the R&D and industrialization of high-quality and differentiated small molecule innovative drugs. The company has built a product pipeline covering multiple disease fields such as hypoglycemic, anticancer, and autoimmune diseases with an integrated drug research and development technology platform and a diversified business perspective. In the field of hypoglycemic drugs, Shenggliptin, the core product independently developed by the company, has submitted an NDA (product launch application) to the National Drug Administration and has been accepted. The results of the Phase 3 clinical trial showed that low doses can reach the predetermined trial endpoint, while the high-dose group can also demonstrate the safety of the drug well. The therapeutic effect of "half the dose" is twice as effective, making it expected to become the best hypoglycemic drug in the class. At the same time, the company has also carried out a comprehensive layout around oral drugs and derivative diseases of various targets related to diabetes. CGT-2201, which was approved for clinical use this time, is one of its pipeline matrix members.

2023-04-20