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News Center

Shengshi Taikang: The Molecular Designer and Their Business Vision

Shengshi Taikang: The Molecular Designer and Their Business Vision

In 2006, Merck’s sitagliptin was officially launched for diabetes treatment, becoming the world’s first approved DPP4 inhibitor. At the time, Yu Qiang, co-founder and CEO of Shengshi Taikang, was running a U.S.-based company focused on applying fragment-based drug discovery technology to deliver drug precursor compounds. After sitagliptin hit the market, Yu Qiang noticed that the compound still had room for improvement in terms of its fit with the target enzyme DPP4. Driven by this insight, his company synthesized numerous compounds targeting the same DPP4 pathway—and subsequently compared them against the publicly available data on sitagliptin. Ultimately, these new compounds demonstrated comparable efficacy to sitagliptin, prompting Yu Qiang to realize that this approach might be heading in the right direction, offering clear opportunities for further optimization.

Time：2020-07-20 09:21

Shengshi Taikе partners with Yunxuan Pharmaceutical to broadly deploy CXCR4 antagonists.

Shengshi Taikе partners with Yunxuan Pharmaceutical to broadly deploy CXCR4 antagonists.

Recently, Shengshi Taikang, which focuses on both internal R&D and strategic external collaborations, announced that it has signed an exclusive cooperation and licensing agreement with Yunxuan Pharmaceutical, securing global exclusive rights for the development and commercialization of a preclinical-stage CXCR4 antagonist—a promising compound targeting chemokine receptor type 4.

Time：2020-04-16 17:16

Shengshi Taikang: Tafamidis Marketing Application Accepted by NMPA

Shengshi Taikang: Tafamidis Marketing Application Accepted by NMPA

Every year, the last day of February marks "International Rare Disease Day." Today, more than 7,000 rare diseases are known worldwide, with 80% having genetic origins. Yet only a few dozen of these conditions can currently be effectively treated or managed with medication. Diagnosing rare diseases remains challenging, and the cost of life-saving treatments is often prohibitively high, leaving patients struggling to survive. At the forefront of rare disease research and development, Shengshi Taikang is dedicated to delivering cutting-edge therapeutic solutions that offer new hope to those battling these debilitating conditions. On this special day, Shengshi Taikang proudly announces that its pioneering oral drug, teriflunomide—developed specifically for treating multiple sclerosis (MS), a rare and chronic autoimmune disorder—has officially received acceptance from China’s National Medical Products Administration for its marketing application.

Time：2020-02-29 08:54

Shengshi Taikang: The first domestically developed, original DPP-4 inhibitor, Sitagliptin, advances from "Phase 2 to Phase 3" without delay.

Shengshi Taikang: The first domestically developed, original DPP-4 inhibitor, Sitagliptin, advances from "Phase 2 to Phase 3" without delay.

Shengshi Taikang Biopharmaceutical Technology (Suzhou) Co., Ltd. is an innovative technology company dedicated to the research and development of antidiabetic drugs. The company’s newly developed phosphate senvogliflozin tablets are a novel DPP-4 inhibitor, boasting high potency and exceptional safety profiles. Notably, the drug was successfully selected twice—in 2012 and 2018—for China’s national key programs focused on the creation of major new medicines during the 12th and 13th Five-Year Plans, respectively. This year, data from a large-scale Phase I clinical trial have demonstrated that, compared to the positive-control drug sitagliptin, Shengshi Taikang’s phosphate senvogliflozin shows promising efficacy and remains safe and reliable for treating type 2 diabetes. Currently, the drug has received official approval from the National Medical Products Administration’s Center for Drug Evaluation, allowing it to skip Phase II clinical trials and proceed directly into Phase III testing.

Time：2019-11-14 17:17

[Ranking] Cyzone 2019 Top 50 Innovative Healthcare and Wellness Companies in China Unveiled—Growing and Innovating Against the Grain Amidst the Capital Winter

[Ranking] Cyzone 2019 Top 50 Innovative Healthcare and Wellness Companies in China Unveiled—Growing and Innovating Against the Grain Amidst the Capital Winter

“The valuation bubble in the healthcare and wellness sector is gradually being deflated, as the market returns to rationality.” When asked about the biggest shift in China’s healthcare and wellness venture capital landscape in recent years, several investors highlighted this very point. They noted that after the investment and IPO boom in the healthcare and wellness industry from 2015 to 2017, the sector is now entering a major reshuffling phase. Both startups and investment firms alike will face a process of survival of the fittest, with the Matthew effect intensifying. Ultimately, only the leading companies and institutions will thrive—and even grow stronger over time.

Time：2019-09-19 09:39

What makes the promising new diabetes drug, senglutide—poised to become the best-in-class—so exceptional?

What makes the promising new diabetes drug, senglutide—poised to become the best-in-class—so exceptional?

Last month, Shengshi Taikang Biopharmaceutical Technology (Suzhou) Co., Ltd. announced the completion of its Pre-A round of financing, revealing that its flagship product, Shengetlin, is poised to become a best-in-class drug in its category. Shengetlin is a novel antidiabetic medication belonging to the class of DPP-4 inhibitors—glucagon-like peptide-1 (GLP-1) receptor agonists. Since Merck introduced sitagliptin, the world’s first DPP-4 inhibitor, to the U.S. market in 2006, DPP-4 has rapidly emerged as one of the most promising targets in diabetes drug development. Over the past few years, several top-10 global pharmaceutical companies have successfully developed multiple next-generation DPP-4 inhibitors, each offering improved efficacy, formulation options, and reduced side effects compared to sitagliptin.

Time：2019-08-23 09:53

Shengshi Taikang Secures Over 100 Million Yuan in A+ Round Funding Led by Hongtai

Shengshi Taikang Secures Over 100 Million Yuan in A+ Round Funding Led by Hongtai

(Suzhou, China – July 30, 2019) Shengshi Taikang Biopharmaceutical Technology (Suzhou) Co., Ltd. has secured a strategic A+ round of financing totaling over 100 million yuan, led by Hongtai Capital with participation from ABC International. This funding will primarily be used to advance the clinical trials of Shengglitine, a new diabetes treatment, as well as accelerate research progress on other innovative drug projects currently in development. Additionally, the company’s rare disease medications, which have already completed consistency evaluations, are set to launch into the market early next year.

Time：2019-07-30 17:23

Focus on the STAR Market: A Survey of Sci-Tech Enterprises in Suzhou Industrial Park—Some Are Charging Ahead, While Others Remain on the Fences

Focus on the STAR Market: A Survey of Sci-Tech Enterprises in Suzhou Industrial Park—Some Are Charging Ahead, While Others Remain on the Fences

Since its launch, the STAR Market has received applications from a total of 65 companies, including five from Suzhou Industrial Park—among them Jiangsu Beiren Robot System Co., Ltd., one of the first batch accepted on March 22, as well as Hejian Chip Manufacturing (Suzhou) Co., Ltd. Additionally, Borei Pharmaceutical, affectionately known as "B Village," recently submitted its listing application. A reporter from First Finance recently visited Suzhou Industrial Park to get an inside look at these innovative enterprises and share their insights with you, dear readers.

Time：2019-04-12 09:56

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